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Human Papillomavirus – What you need to know

Human Papillomavirus (HPV) is a family of very common and contagious viruses. There are more than 100 different types of HPV and while most are usually harmless, some can cause genital warts and some can lead to cervical cancer.

HPV is one of the most common sexually transmitted infections in Canada and in the world today. Unfortunately most sexually active people who have HPV are unaware that they have it, so the infection is often passed on to partners without even knowing it.

A vaccine is now available for girls in grade 8 that will protect them from HPV types 16 and 18, which are responsible for an estimated 70 per cent of cervical cancers, as well as types 6 and 11, which cause 90 per cent of genital warts.

The vaccine is a three-part series that will again be offered to grade 8 girls with signed consent forms in Simcoe Muskoka schools this fall. Grade 8 girls who have received at least one dose of the three-dose HPV vaccination series in their grade 8 year may complete the series as part of the publicly funded program during their Grade 9 year.

While the vaccine is currently only funded for girls in grade 8, it is available at a fee of about $400 through health care providers. Some insurance companies cover the cost of the vaccine.

 

 

What is HPV?

Human papillomavirus, or HPV, is a family of more than 100 common viruses. Most types of HPV are harmless, have no signs or symptoms and clear up by themselves. Some of the low-risk types of HPV can cause common skin warts and plantar warts (warts on the soles of the feet). Other types of the virus are sexually transmitted and affect the area on the genitals and the anus; some types of the virus can cause genital warts, while some high-risk types of HPV can lead to cervical cancer and have been linked to other genital cancers.

HPV is one of the most common sexually transmitted viruses in Canada and in the world today. HPV is so widespread that more than 50 per cent of women and men will have this type of infection at one point of their life or another, and at any given time between 15 and 40 per cent per cent of women will have HPV. About the same proportion of Canadian men are believed to have HPV.

According to the Canadian Cancer Society/National Cancer Institute of Canada, about 1,350 women will be diagnosed with cervical cancer this year and another 390 will die from the disease. The Society of Obstetricians and Gynaecologists of Canada (SOGC) states that thousands more women will be diagnosed with pre-cancerous conditions and more than 400,000 will receive abnormal Pap test results.

HPV can infect anyone who has had a sexual encounter, even without intercourse and penetration. The most common transmission is through vaginal, anal, and oral sex, or skin-to-skin contact of the genitals.

The types of HPV that can cause cancer are often a “silent infection”. They have no obvious signs or symptoms and most people will not even know they are infected. For women, the main concern is infection of the cells of the cervix. These infections can lead to changes in the cervical cells that can be detected as the result of a Pap test.

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The Vaccine

A vaccine is now available to help prevent four types of HPV. These include types 6 and 11, which are two ‘low-risk’ types responsible for an estimated 90 per cent of genital warts, and types 16 and 18, ‘high-risk’ types responsible for an estimated 70 per cent of cervical cancers.

The HPV vaccine currently approved is called Gardasil ®. It can be given to girls and young women ages nine to 26 years. This vaccine is currently not available for males, although there are studies being completed to determine effectiveness of the vaccine on this population.

The vaccine requires three shots. The second shot is given two months after the first dose, and the third is given six months after the first dose. The complete series should be given within 12 months. It is not known at this time if there will need to be a booster in the future.

Although the vaccine is currently only publicly funded for girls in grade 8, the vaccine is available through health care providers for approximately $400. Some insurance companies provide coverage for this vaccine. To determine if this vaccine is covered by your health care plan, contact your provider and provide them with the product DIN : 02283190.

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Public Funding

The HPV vaccine is publicly funded for girls in grade 8. This means that the vaccine will be paid for by the Ontario government for any girl in grade 8 who has provided a signed consent form. Grade 8 girls who have received at least one dose of the three-dose HPV vaccination series in their grade 8 year may complete the series as part of the publicly funded program during their Grade 9 year.

Those who wish to receive the vaccine from their health care provider will have to pay for the vaccine. Students who are unable to receive the vaccine at school will be able to make an appointment with the health unit to receive the funded vaccine at a health unit clinic. For questions regarding public funding, call the vaccine preventable disease team at 705-721-7520 or 1-877-721-7520 ext. 8806.

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Pap Testing and Screening

A Pap test (also called a Pap smear), checks for changes in the cells of the cervix. The cervix is the lower part of the uterus (womb) that opens into the vagina (birth canal). The Pap test indicates if there is an infection, abnormal (unhealthy) cervical cells, or cervical cancer. The vaccine is not a replacement for a Pap test and does not prevent the spread of all types of HPV or other sexually transmitted infections. Education about prevention and protection remain important for teens and young adults.

A woman should have her first Pap test within three years of becoming sexually active, and then every two years after that or as recommended by her health care provider. A Pap test is the only way to detect abnormal cells in the cervix. An abnormal Pap test may mean that there are precancerous cells that have a small chance of developing into cancer. These can be treated successfully at this stage because the progression to cancer is slow, and can take years.

There are no tests available to detect the HPV virus. Most people will have contracted an HPV infection before the age of 50, but will never have known that they had HPV because their infection was harmless, had no symptoms and cleared up by itself.

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How to Protect Yourself

  • Anyone who has sex is at risk for HPV. Since not all infections have symptoms or noticeable symptoms, you often cannot tell if you are infected.
  • Abstaining from sex or limiting your number of sexual partners will decrease your chances of contracting HPV.
  • If you are a female or have young female children between nine to 26 years of age, consider the HPV vaccine.
  • See your doctor regularly for a Pap test - even if you have been vaccinated for HPV.
  • Learn about sexually transmitted infections (STI ’s) including their signs, symptoms, consequences and the ways they are spread. Learn about and always practice safe sex.
  • Encourage new sexual partners to be tested for all STIs before you have sexual contact.
  • Make informed decisions about your sexual health. Talk to your partner about their STI status and the use of protection. Remember that the previous sexual behaviour of your partner translates into a risk for you, especially if they have had multiple partners.
  • The use of latex and polyurethane condoms may reduce your risk of getting HPV, as well as preventing other STIs. However, remember that those areas of skin not covered by a condom are not protected from HPV.
  • If you have had multiple sexual partners, talk to your doctor about HPV and other STIs you may have been exposed to.

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FAQs

 

Who should get HPV vaccine?

The vaccine is approved for females between the ages of nine and 26 years of age. The vaccine is best for females before they become sexually active and are potentially exposed to HPV.

The health unit is providing the vaccine free to girls in grade 8. Other females can go to their doctor or health care provider and pay for the vaccine. Some private insurance companies may cover the cost of the vaccine.

 

Who should not get the HPV vaccine?

 A health care provider may delay or decide not to give the vaccine to:

  • Anyone with a high fever or serious infection worse than a cold. They should delay having the vaccine until they are better.
  • Anyone who has had a serious reaction (anaphylaxis) to this vaccine in the past.
  • Anyone with a severe allergy to any component of this vaccine: Gardasil ® contains: aluminum, sodium chloride, L-histidine, polysorbate-80, sodium borate.
  • Anyone who has a disease or is taking a medication that lowers the body’s ability to fight infections should seek the advice of their healthcare provider.
  • Pregnant women.

 

What are the side effects of the vaccine?

Serious side effects are rare. The most common side effects of this vaccine include pain, redness, swelling and itching where the needle was given. Other common side effects can include headache, fever, nausea and dizziness.

This is not a complete list of side effects. You should always discuss the risks and benefits of any vaccine with your health care professional.

Acetaminophen or ibuprofen may be taken to reduce discomfort or fever. Always follow package directions. Acetylsalicylic acid (ASA or Aspirin®) must not be given to children under 18 years of age. If symptoms worsen or continue please seek medical attention and notify the health unit.

 

Why is this vaccine important?

HPV viruses are very common. So much so that more than 50 per cent of women and men will have this type of infection at one point of their life or another, and between 15 and 40 per cent of women have HPV at any one time. About the same proportion of Canadian men are believed to have HPV.

According to the Canadian Cancer Society/National Cancer Institute of Canada, about 1,350 women will be diagnosed with cervical cancer this year, and another 390 will die from the disease. The Society of Obstetricians and Gynaecologists of Canada (SOGC) states that thousands more women will be diagnosed with pre-cancerous conditions and more than 400,000 will receive abnormal Pap test results.

 

How effective is this vaccine?

The HPV vaccine provides protection against infection from HPV types 6, 11, 16, and 18. When the proper recommended schedule is followed, the HPV vaccine is almost 100 per cent effective against diseases caused by the HPV types in the vaccine. (The vaccine types are responsible for approximately 70% of cervical cancers and 90% of genital warts). Any deviation from the recommended schedule such as missed or late doses, or previous infection with one or more types of HPV included in the vaccine, may lessen the effectiveness of this vaccine. HPV vaccine does not provide treatment for HPV-related disease. If a girl or woman is already infected with one of the HPV types included in the vaccine she will not be protected from that type of HPV infection or disease that may result from that infection. But it is still worth while receiving the vaccine since it will offer protection again the other types.

 

What is in the vaccine?

Along with the active HPV ingredient are the following inactive ingredients:

  • Aluminum – used to enhance the direct immune response of the vaccine in the body
  • Sodium chloride – salt water
  • L-histidine – amino acid
  • Polysorbate-80 – emulsifying agent
  • Sodium borate – stabilizing agent
  • Yeast – used to culture the virus – not used in the final production of the vaccine.

These components are included in the composition and manufacturing of the vaccine to ensure its effectiveness. For more detailed information on the vaccine components contact Merck Frosst at (514) 428-8600, 1-800-567-2594 or http://www.merckfrosst.ca/mfcl/en/global/contact.html

 

How long has the vaccine been available?

The Gardasil ® vaccine was licensed in Canada in the summer of 2006. The vaccine has previously been licensed in countries including the United States, Great Britain and Australia.

 

How many doses of the vaccine are needed?

The vaccine requires three doses to be given over six months. The first dose should be given at a chosen date, the second dose two months after the first (minimum one month) and the third dose six months after the first (minimum three months). If a dose is missed or given late, it is recommended that all three doses be given within 12 months of the initial dose.

 

Is there a fee for the vaccine?

There is no fee for the vaccine for Ontario girls in grade 8. Grade 8 girls will receive the vaccine through the publicly funded school program, provided they have a signed consent form.

There is a fee for the vaccine for those who are not in grade 8 this school year. The cost for the vaccine series is about $400. Some health plans may cover the cost of the vaccine. To determine if this vaccine is covered by your health care plan, contact your provider and give them the product DIN : 02283190.

 

Does my child have to get the vaccine?

NO. The HPV vaccine is not mandatory. It is up to you and your daughter to decide if she will receive the vaccine or not. Review the information about HPV, as well as the vaccine, so that you can make an informed decision.

 

Is there an alternative to the vaccine?

Protection from HPV can be increased by use of a condom during sexual activity, however it does not provide complete protection. HPV is spread through skin-to-skin contact and a condom may not protect all areas of contact. Abstaining from sex or limiting your number of sexual partners will decrease your chances of contracting HPV. Encourage new sexual partners to be tested for all sexually transmitted infections before you have sexual contact.

 

I have an older child, is the vaccine free for them?

No. The HPV vaccine is not publicly funded for children who are not in grade 8. Your child can receive the vaccine at a cost from your physician or health care provider.

 

Can my child have the vaccine at my doctor’s office?

You can make arrangements to have the HPV vaccine at your doctor’s office, however it is not publicly funded for anyone other than grade 8 girls. This means that the vaccine will have a fee. Some health insurance companies may provide coverage for this vaccine. This vaccine is only publicly funded for the grade 8 school program offered by the local public health unit.

 

What if my child misses a dose at the school?

If your child misses a dose at the school clinic for unforeseen reasons your child can receive the missed dose at the health unit. It is the responsibility of the student or parent to book the appointment with the health unit to receive the missed dose of the vaccine. It is important to remember that the vaccine is not complete until three doses have been given and that the three doses should be given within one year of the first dose.

 

If I choose not to let my child get the vaccine in grade 8, can she have it later?

If you choose not to have your child vaccinated in grade 8 your child will not receive the vaccine in the publicly funded program. Your child may receive this vaccine through their health care provider at a cost. The vaccine is presently only funded through the school program for female students in grade 8.

 

Why are the grade 8 students getting the vaccine and not all teenage girls?

The province made the decision to provide the HPV vaccine to female students in Grade 8 after evaluating details, including where the vaccine will be most beneficial and cost effective. The vaccine will be available at a cost for girls who are not presently in Grade 8. The vaccine program is intended to run for a minimum of three years, which means that if your child will be in Grade 8 during that three-year window, they will be able to receive the vaccine through the school immunization program.

 

Does my child need this vaccine if they are not sexually active?

The HPV vaccine is most effective before girls become sexually active, and before they have been exposed to HPV. The HPV vaccine can help prevent the two strains most responsible for genital warts and help prevent the two strains most responsible for cervical cancer, but it is not a treatment for HPV. It is important to reinforce safe and healthy sexual behaviour with our children before and after they become sexually active, regardless of whether or not they receive the HPV vaccine.

 

Can my son receive the vaccine?

The HPV vaccine is not licensed to be given to boys at this point in time. Vaccine trials are currently being conducted to determine if the vaccine is effective in preventing HPV in boys. Presently the goal of the HPV vaccine is to prevent cervical cancer in girls and women.

 

Will my child need a booster in the future?

At this time the vaccine is a three-dose series. It is not known if a booster shot will be required in the future.

 

Does the vaccine replace regular health screening and testing?

NO. The vaccine only protects against four types of HPV. There are many other types of HPV strains that may cause infection, as well as other STIs. Regular pap tests and screening are important for sexual health, as are safe sex practices and education.

 

If I am already infected is the vaccine safe to receive?

Yes. The vaccine is still safe to receive as it is unlikely that you are infected with all the types of HPV the vaccine provides protection for. Testing to see if you are already affected by one of the types of HPV included in the vaccine is not widely available. HPV is not treated by the vaccine.

 

Can I still get cervical cancer if I get this vaccine?

Yes. The vaccine only provides protection against HPV types 16 and 18, which cause 70 per cent of all cervical cancers. Infection caused by other ‘high-risk’ types of HPV can still lead to cervical cancer, so it is still important that women continue to follow their doctor’s recommendations for regular Pap tests, which screen for cervical cell changes leading to cervical cancer.

 

Will the vaccine protect against other STI ’s like Human Immunodeficiency Virus (HIV) or Herpes Simplex Virus (HSV)

No. Although the names appear to be similar and both are sexually transmitted infections, the HPV vaccine will not provide any protection from these or any other STIs. It is important to inform and educate, as well as maintain and encourage safe sex practises, to provide protection from these and other STIs.

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Where do I go for more information?

 

 

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  September, 2008
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